ARGIRELINE
(acetyl hexapeptide-8)

Argireline (acetyl hexapeptide-8) is a powerful anti-aging peptide often referred to as "Botox in a bottle." It works by relaxing facial muscles, reducing the appearance of fine lines and dynamic wrinkles—especially on the forehead and around the eyes. By inhibiting neurotransmitters that trigger muscle contractions, Argireline helps prevent wrinkle formation without the need for injections. It also improves skin hydration, elasticity, and smoothness. Suitable for all skin types, Argireline offers a gentle, non-invasive alternative to Botox with consistent use. It’s a popular choice in serums and creams for visibly younger, smoother, and more rejuvenated skin.

Benefits

Reduces Fine Lines and Wrinkles

Particularly effective on dynamic wrinkles (from facial expressions)
Commonly targets forehead lines and crow’s feet

Botox-like Action (Non-Invasive)

Relaxes facial muscles by inhibiting neurotransmitters
Mimics Botox without needles or clinical procedures

Prevents New Wrinkle Formation

Helps stop deepening of expression lines over time with regular use

Hydrates and Plumps the Skin

Improves skin moisture retention for a smoother appearance

Improves Skin Elasticity and Firmness

Enhances overall skin texture and resilience

Gentle and Safe for Daily Use

Suitable for sensitive skin and long-term use
Low risk of side effects when applied topically

Fast-Acting

Visible softening of wrinkles often within 2–4 weeks of consistent use

Pairs Well with Other Ingredients

Works synergistically with hyaluronic acid, peptides (like Matrixyl), and niacinamide

Side Effects

Mild Skin Irritation

Redness, dryness, or slight itching—especially in sensitive skin
Often due to the product base or additional ingredients

Allergic Reaction (Rare)

Tingling, rash, or swelling
Discontinue use if any of these occur

Over-Relaxation of Facial Muscles (Very Rare)

In extremely high concentrations or overuse, may cause mild muscle laxity or a “droopy” look
Typically reversible upon stopping use

Not Recommended for Use with Needling

Argireline affects neuromuscular activity and is not ideal for microneedling or injections
It is designed strictly for topical use

Usage Tips to Minimize Side Effects

Patch test before full use (especially near eyes)
Use concentrations of 5–10% for best balance of efficacy and safety
Avoid using with acids or exfoliants at the same time to prevent irritation

Dosage

Recommended Concentration

5% to 10% is the typical effective range in skincare products
- 5% for maintenance, sensitive skin, or around the eyes
- 10% for deeper lines or more intensive results

Application Frequency

Twice daily: Morning and evening, after cleansing and before moisturizer
Use consistently for at least 2–4 weeks to start seeing visible results

Where to Apply

Forehead lines
Crow’s feet (outer eye area)
Smile lines (nasolabial folds)
Neck creases (optional)

How to Use

Cleanse and tone your face.
Apply 1–2 pumps or a pea-sized amount of Argireline serum to targeted areas.
Allow to absorb before applying other serums, creams, or sunscreen.

Important Tips

Do not microneedle or inject Argireline – it is not intended for that use.
Avoid combining with strong acids or retinoids in the same routine unless tolerated well.
Store in a cool, dark place to preserve peptide stability.

Medical Disclaimer: These guidelines are for educational purposes only. Always consult a licensed medical professional before starting any peptide therapy.

ARGIRELINE (acetyl hexapeptide-8)