SEMAX

Semax is a potent nootropic peptide with remarkable benefits for brain health and cognitive enhancement. Originally developed in Russia, it boosts memory, focus, and mental clarity by increasing levels of brain-derived neurotrophic factor (BDNF), essential for neuroplasticity and learning. Semax also enhances blood circulation in the brain, improves oxygen utilisation, and protects neurons from stress and damage. It has antidepressant and anxiolytic properties without sedation or dependency. Additionally, Semax supports faster recovery from brain injuries, fatigue, or mental burnout. With its fast-acting and neuroprotective effects, Semax is a powerful tool for optimising brain performance, resilience, and long-term cognitive vitality.

Benefits

Enhances Cognitive Function

Improves focus, mental clarity, and processing speed
Boosts learning capacity and information retention

Improves Memory

Supports both short-term and long-term memory formation
Promotes synaptic plasticity and brain efficiency

Increases BDNF (Brain-Derived Neurotrophic Factor)

Stimulates neuroplasticity, brain repair, and growth of new neurons
Supports long-term brain resilience and adaptability

Neuroprotective Effects

Protects neurons from oxidative stress, ischemia, and toxicity
Supports recovery from brain injury or neurological damage

Reduces Mental Fatigue

Increases mental endurance during high cognitive load
Helps combat brain fog and burnout

Supports Mood and Emotional Stability

Exhibits antidepressant and anxiolytic effects without sedation or addiction
Helps regulate stress responses via the central nervous system

Improves Cerebral Blood Flow

Enhances oxygen and nutrient delivery to brain tissue
May support clarity and alertness, especially in fatigue states

Supports ADHD and Mood Disorders (Experimental)

May improve focus, impulse control, and executive function in attention disorders
Can assist with low motivation or mood imbalance

Side Effects

Mild and Common Side Effects

Nasal irritation (dryness, itching, or burning sensation)
Mild headache
Temporary increase in anxiety or restlessness (especially at high doses)
Dizziness or light-headedness
Dry mouth or thirst

Less Common or Reported Reactions

Mood swings or irritability in sensitive individuals
Insomnia or trouble sleeping if taken too late in the day
Nausea or upset stomach (rare, more likely with subcutaneous use)

Unknown Long-Term Risks

Long-term studies in humans are limited
Not recommended during pregnancy or breastfeeding

General Safety Notes

Non-toxic and non-addictive
No known risk of withdrawal or tolerance with short-term use
Often preferred over stimulant-based nootropics due to low side effect profile

Dosage

Most Common Route: Intranasal Administration

Standard Dose:

300 mcg to 600 mcg per dose
Can be increased up to 1 mg per dose for therapeutic or intensive cognitive support

Frequency:

1–2 times daily, depending on individual needs
- Once daily for general nootropic use
- Twice daily for high cognitive demand, recovery, or therapeutic support

Cycle Length:

10–14 days on, followed by a 1–2 week break
For longer use: 5 days on, 2 days off per week (to avoid desensitisation)

Administration Tips:

Divide dose between nostrils (e.g., 300 mcg = 150 mcg per nostril)
Apply on an empty stomach for best absorption
Avoid use after 5 PM to prevent overstimulation or sleep disruption
Store in a refrigerator (2–8°C) to maintain potency

Alternative Route (Less Common): Subcutaneous Injection

Dose: 100–300 mcg once daily
Not widely used due to excellent intranasal bioavailability

Tips:

Store peptide in the refrigerator (2–8°C) once reconstituted.
Use bacteriostatic water for reconstitution.
Always follow aseptic injection protocols.

Medical Disclaimer: These guidelines are for educational purposes only. Always consult a licensed medical professional before starting any peptide therapy.