DIHEXA
Dihexa is a powerful nootropic peptide known for its exceptional benefits in enhancing brain health and cognitive function. Originally developed to treat neurodegenerative conditions, Dihexa promotes the formation of new synaptic connections, improving memory, learning, and mental clarity. It significantly boosts brain-derived neurotrophic factor (BDNF), supporting neurogenesis and long-term brain plasticity. Dihexa has shown promise in reversing cognitive decline, improving executive function, and aiding recovery from brain injuries or neurodegeneration. Unlike stimulants, it works at the structural level, helping repair and optimise neural pathways. With its regenerative properties, Dihexa is a cutting-edge solution for lasting cognitive enhancement and brain longevity.
Benefits
Enhances Memory and Learning
​
-
Improves short- and long-term memory formation
-
Boosts information retention and cognitive recall
-
Useful for age-related cognitive decline and memory impairment
Promotes Synaptogenesis
​
-
Stimulates the formation of new synaptic connections in the brain
-
Supports overall neural network growth and repair
Increases BDNF (Brain-Derived Neurotrophic Factor)
​
-
Supports neuroplasticity, learning, and resilience to stress
-
Encourages brain regeneration and adaptability
Improves Executive Function
​
-
Enhances focus, attention span, decision-making, and task organisation
-
May support individuals with ADHD or cognitive fatigue
Neuroprotective Properties
​
-
Helps protect neurons from oxidative damage, inflammation, and degeneration
-
Potentially useful in conditions like Alzheimer’s, Parkinson’s, or traumatic brain injury
Supports Recovery from Brain Injury
​
-
May accelerate healing from stroke, TBI, or neuroinflammation
-
Enhances repair of damaged brain tissue
Non-Stimulant Cognitive Enhancement
​
-
Improves brain function without overstimulation, jitteriness, or crash
-
Suitable for long-term use under medical guidance
Potential Longevity Benefits
​
-
By promoting healthy neural function and reducing degeneration, Dihexa may support brain aging prevention and extended cognitive lifespan
Side Effects
Mild and Reported Side Effects
​
-
Headache (most common, especially at higher doses)
-
Insomnia or overstimulation (if taken too late in the day)
-
Irritability or restlessness in some individuals
-
Increased anxiety (rare, dose-dependent)
-
Dry mouth or thirst
-
Digestive discomfort (nausea, upset stomach in sensitive users)
Theoretical or Unconfirmed Risks
​
-
Unregulated synaptogenesis – may lead to abnormal neural activity if overused (based on animal data)
-
Unknown effects on long-term brain function, especially with chronic or high-dose use
-
Hormonal changes – no consistent evidence, but under investigation
Not Recommended For
​
-
Pregnant or breastfeeding individuals
-
People with a history of seizure disorders or bipolar disorder (due to unknown neurological effects)
Safety Considerations
​
-
Dihexa is not FDA-approved for human use
-
Should only be used under medical supervision
-
Start with low doses and titrate slowly to assess tolerance
Dosage
Common Oral Dosage (Most Practical Form)
Standard Dose:
​
-
4–10 mg per day (orally or sublingually)
Typical Starting Dose:
​
-
2–5 mg per day, titrate upward based on response
Maximum Studied Range (Anecdotal Use):
​
-
Up to 20 mg per day, though higher doses increase risk of side effects
Frequency & Cycle
​
-
Once daily, preferably in the morning to avoid sleep disturbance
-
Some protocols use 5 days on / 2 days off to reduce adaptation
-
Suggested cycle: 4–8 weeks on, followed by 2–4 weeks off
Other Forms (Less Common)
​
-
Topical/transdermal: May be compounded in creams for localised or systemic absorption
-
Injectable: Rare and not recommended due to lack of safety data
Safety Tips
​
-
Avoid taking late in the day (may cause insomnia)
-
Monitor for headaches, irritability, or overstimulation
-
Store in a cool, dry place, ideally refrigerated if in solution form
Medical Disclaimer: These guidelines are for educational purposes only. Always consult a licensed medical professional before starting any peptide therapy.
