NAD+
(Nicotinamide Adenine Dinucleotide)
NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme that plays a key role in cellular energy production, DNA repair, and longevity. As we age, NAD+ levels decline, leading to fatigue, slower metabolism, and cognitive decline. Supplementing with NAD+ peptide helps boost mitochondrial function, enhances mental clarity, and improves physical performance. It supports healthy aging by activating sirtuins, the body’s natural longevity genes, and reducing oxidative stress. NAD+ therapy is also known to improve sleep quality, skin health, and metabolic function. Whether for anti-aging, recovery, or energy, NAD+ is a powerful tool for cellular rejuvenation and whole-body vitality.
Benefits
Cellular Energy & Mitochondrial Support
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Enhances ATP production (cellular energy)
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Boosts mitochondrial function and efficiency
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Reduces fatigue and improves physical performance
Cognitive & Neurological Health
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Improves mental clarity, focus, and memory
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Supports brain cell repair and neuroprotection
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May help in neurodegenerative conditions (e.g., Alzheimer’s, Parkinson’s)
Anti-Aging & Longevity
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Activates sirtuins, the body's longevity-regulating proteins
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Promotes DNA repair and genomic stability
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Delays age-related decline in metabolism and function
Metabolic & Weight Support
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Improves insulin sensitivity
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Enhances fat metabolism
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Supports healthy weight management
Skin, Sleep & Recovery
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May improve skin texture and elasticity
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Enhances sleep quality
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Speeds up cellular and muscle recovery post-exercise or injury
Other Health Benefits
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Supports cardiovascular health
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Reduces inflammation and oxidative stress
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Aids in detoxification and liver support
Side Effects
Common (Usually Mild and Temporary):
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Nausea
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Headache
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Fatigue or feeling flushed during or after administration
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Digestive upset (bloating, cramping, diarrhea—mostly with oral forms)
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Warmth or facial flushing (especially with IV or high-dose injections)
Less Common or Dose-Dependent:
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Lightheadedness or dizziness
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Muscle cramps (from rapid infusion or high dosing)
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Increased anxiety or restlessness (rare, typically from fast IV drip rates)
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Low blood pressure (due to vasodilation effects during IV administration)
Important Notes:
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Most side effects occur with IV therapy when NAD+ is administered too quickly—slower drips typically reduce discomfort
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Starting with low doses and gradually increasing can help improve tolerance
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Oral NAD+ or precursors (like NMN or NR) tend to have fewer side effects but may be less effective than IV or subcutaneous injection.
Dosages
1. IV NAD+ Therapy (Most Potent & Rapid Effect):
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Dosage: 250 mg to 1000 mg per session
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Frequency: 1–3 times weekly initially, then monthly for maintenance
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Infusion Rate: Slow drip over 1–3 hours to minimize side effects
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Use: Energy, detox, addiction support, longevity, neurological health
2. Subcutaneous (SC) Injection:
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Dosage: 50 mg to 200 mg per day
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Frequency: Daily or 3–5x/week
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Use: Anti-aging, cognitive boost, energy, mitochondrial health
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Often stacked with other peptides or B12 for synergistic effect
3. Intramuscular (IM) Injection:
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Dosage: 100 mg to 300 mg per shot
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Frequency: 2–3x per week or as needed
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Use: Quick energy, mood lift, recovery enhancement
4. Oral NAD+ Precursors (e.g., NMN or NR):
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NMN: 250–500 mg daily (up to 1,000 mg for advanced protocols)
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NR: 250–300 mg daily
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Use: Long-term maintenance of NAD+ levels
Important Notes:
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Start low and titrate up to avoid flushing, fatigue, or nausea
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Drink plenty of water during IV or injection protocols
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Monitor for tolerance if combining with exercise, stimulants, or other mitochondrial peptides
Medical Disclaimer: These guidelines are for educational purposes only. Always consult a licensed medical professional before starting any peptide therapy.